Vetoryl Killed My Dog – Can Vetoryl Kill My Dog?

Is Vetoryl safe for dogs? This question has been asked on social media sites frequently. Dogs and other animals have been killed by it, while others have said it has worked well for them. Why is this happening? Do you know if Vetoryl is being banned or if it is being recalled due to its deadly effects on dogs?

My dog was killed by Vetoryl. My dog’s health conditions were aggravated by the medication, which led to his death. Vetoryl can have serious side effects that I was unaware of.

Vetoryl killed my dog while he was being treated. This is why I would like to share my experience with other pet owners so that they can be aware of the risks involved with this drug and make the best decision when it comes to their pets’ health.

Last week, after being prescribed Vetoryl, I lost my beloved dog. Despite the fact that we believe he had Cushing’s Disease for many years, he was only diagnosed with it a year ago.

As soon as we noticed he was panting excessively, even while sleeping, we decided to discontinue the medicine for a few days. He then started sweating more and was unable to sleep without it.

He shivered and was barely able to get up the next day. A vet did an ultrasound and found that his liver was failing, so we rushed him to the emergency room.

The doctors offered us several choices: euthanasia, blood transfusions (which only bought him a few days), or hospitalization with fluids and possibly surgery for 5-7 days. Despite Max’s alertness and responsiveness, he appeared normal from the outside, so I chose the hospital option. The doctors recommended euthanasia after three days in the hospital.

Also Read: Raw diet killed my dog – Can Raw diet Kill Dogs?

Can dogs take Vetoryl?

It is recommended you follow the directions carefully and only use Vetoryl® as prescribed. Vetoryl® is generally well tolerated by most dogs. Due to the many side effects that have been reported, however, dog owners are leery about using this prescription drug.

Vetoryl is associated with the following symptoms: Breathing rapidly, Incoordination, Lethargy, Seizures, Diarrhea, and vomiting, and A general feeling of malaise.

When your dog is taking any new medicine, you need to watch them closely to make sure there are no negative side effects. The side effects of some medications can be serious and require immediate attention, so it’s important to know what to look for.

Cushing’s Disease: What Is It?

A dog with Cushing’s disease has hormonal problems. A tumor on the pituitary gland or the adrenal glands can cause overproduction of cortisol, which leads to this disease.

There are a variety of symptoms associated with Cushing’s disease, including hair loss, obesity, muscle wasting, diarrhea, and vomiting.

Other serious health problems caused by this disease include high blood pressure, liver disease, diabetes, and congestive heart failure.

You can choose from two types: adrenal- or pituitary-dependent.

Adrenal-mediated – Cushing’s disease caused by adrenal-dependent tumors is located near the kidneys and is caused by tumors of the adrenal glands. Twenty percent of dogs who suffer from Cushing’s disease have this condition.

Pituitary-dependent – Cushing’s disease which is caused by a tumor on the pituitary gland is more common. About 80 percent of cases of Cushing’s disease in dogs are caused by this type.

Also Read: Metronidazole killed my dog – Can Metronidazole Kill Dogs?

Is Cushing’s Disease Common in Dogs?

About 100,000 dogs are diagnosed with Cushing’s disease in the United States every year. Dogs over 6 years of age are most likely to contract Cushing’s disease, but it can also affect dogs younger than 6.

How does Vetoryl affect a dog if it gets too much of it?

When a dog overdoses on Vetoryl, he becomes lethargic, vomits, and has seizures. There are times when side effects can be life-threatening.

Among Vetoryl’s main ingredients is trilostane, which inhibits the adrenal glands’ production of cortisol. Cushing’s disease can be effectively treated with this method, but there are some risks. Overdosing your dog on Vetoryl without realizing it can be one of these risks.

He died after I gave him Vetoryl twice a day. Those are the facts. For my dog’s Cushing’s disease, my vet prescribed Vetoryl. His condition deteriorated as he urinated in the house, panted, and lost weight. Consequently, I asked my veterinarian whether this medicine was safe to give him over the long-term, and he said that this wouldn’t harm his liver the way the other drug (Lysodren) might.

My dog passed away on January 26th. The thought never occurred to me until after he passed away that there are many other people out there whose dogs have died from this drug too.

Vetoryl interacts with what drugs?

If your dog has lung, liver, kidney, or diabetes mellitus, you should use trilostane cautiously. Vetoryl® (trilostane) should also be given in consultation with your veterinarian if your pet is taking any other medications. Vetoryl may also interact with: ACE inhibitors, Aminoglutethimide, Ketoconazole, and Spironolactone is a potassium-sparing diuretic.

Also Read: Prednisone killed my dog – Can prednisone Kill My Dog?

Cushing’s Disease Symptoms And Signs?

There is no single sign or symptom of Cushing’s disease in dogs. Here are some of the most common signs: Loss of hair, Muscle wasting, Diarrhea, Vomiting, Obesity, Increased thirst and urination, Increased hunger, and Low energy.

It is commonly associated with excessive thirst, urination, and appetite, as well as hair loss and thinning skin in dogs.

Some dogs may also develop a potbelly or thin out around their heads and necks. Seizures, vomiting, and diarrhea may be more common in more severe cases.

Here are some reviews

Pet owners are impressed by the effectiveness of Vetoryl, with many saying it helped keep their pets healthy for years. Most dogs don’t mind taking the capsules, and they are easy to administer.

The high price of Vetoryl is, however, a source of concern. In many cases, owners switch medications because they could no longer afford them. Many report stomach upset and diarrhea as side effects.

Check out our review of the best dog adrenal supplements for an affordable treatment option.

1. I have tried a lot of products, but Vetoryl seems to be the only one that does not make my dog sad. My dog cannot live without it. He was almost going to die from hyperthyroidism, but fortunately, Vetoryl has kept him alive longer than originally expected.

2. My dog did not die from Vetoryl. It was a difficult time for him because his adrenal glands were failing when he was 13 years old. His death was inevitable. He was saved by vetoryl. From being grumpy and lethargic, he became playful and happy.

Vetoryl is relatively cheap in comparison to other drugs that come with similar side effects to Vetoryl, but with less success. No disrespect meant – I simply feel sorry that your dog had problems with this drug since it gave my dog such a good quality of life until he passed away.

3. I have been using Vetoryl to treat my Cushing’s dog. I am pleased with the results. There was an initial side effect of diarrhea, but that has since gone away. If you are having problems with your pet, I highly recommend this product. My friends who have older dogs have recommended it to me, and I will continue to recommend it to them.

4. Her symptoms have improved greatly over the years, and I believe it does work since I’ve used it for about two years. The treatment does require a prescription from a veterinarian, and side effects include panting and some diarrhea that can be controlled with diet changes and probiotics. The treatment is generally satisfactory.

Also Read: Freshpet Killed My Dog – Can Freshpet Kill My Dog?

Can Cushing’s Disease be fatal?

Although Cushing’s disease can be serious and life-threatening, most dogs will live for a number of years after being diagnosed with the disease.

Depending on the severity of each dog’s symptoms and the response to treatment, it’s possible to predict the outcome of each case.

Dogs with Cushing’s disease can live longer if they receive effective treatment.

It is common to remove either the affected pituitary gland or adrenal gland in Cushing’s disease, depending on which organ produces cortisol.

Radiation and surgery can also be used to remove the tumor in some cases.

What causes death in dogs with Cushing’s?

It progresses slowly in dogs with Cushing’s. As a result of leaving dogs untreated, they develop higher risks for hypertension; pulmonary thromboembolism, which leads to sudden death; congestive heart failure; neurological problems; blindness; and myopathy.

Is there an alternative to Vetoryl?

 For the management of pituitary dependent Cushing’s disease, two medications are commonly used: Lysodren® (also called Mitotane or o,p’-DDD) and Trilostane (brand name Vetoryl®).

Also Read: Can Rimadyl killed my dog? All You Should Know

What are the side effects of Vetoryl for dogs?

Poor/reduced appetite, vomiting, lethargy/dullness, diarrhea, and weakness are the most common adverse reactions. The drug may cause more serious reactions, including severe depression, hemorrhagic diarrhea, collapse, hypoadrenocortical crisis, and adrenal necrosis or rupture, and may result in death.

What are the end stages of Cushing’s disease in dogs?

They become weak and lose muscle as the disease progresses. On the flanks, neck, and perineum, owners may notice thinning of the skin, lesions on the skin, and hair loss. Fatigue and obesity are also common complaints.  

Is Cushing’s painful for dogs?

In dogs with Cushing’s disease (especially if uncontrolled), the following symptoms can occur High blood pressure. Infections of the kidneys. Stones in the bladder.

Can Vetoryl stop working?

Vetoryl is generally required for the rest of the patient’s life once they begin treatment. As a result, unless your veterinarian instructs you otherwise, you should continue to administer Vetoryl at the dose and frequency recommended by your veterinarian.

Also Read: Benadryl killed my dog – Can dogs die from Benadryl?

Is there a generic for Vetoryl for dogs?

Veterinarians use Trilostane most commonly to treat Cushing’s disease in dogs (and less often in cats as well). The FDA has approved Trilostane under the brand name Vetoryl® and as generic Trilostane.

Is Vetoryl the same as trilostane?

Alopecia X (Canine hyperadrenocorticism) and hyperadrenocorticism (Cushing’s disease) are treated with trilostane (trade names: Vetoryl®, Desopan®, Modrastane®, or Modrenal®).

Can you stop Vetoryl in dogs?

Be sure your dog continues to receive Vetoryl® on a daily basis as prescribed.  You should not stop the treatment of your dog even if you notice a dramatic improvement in his health – for example, he has a normal appetite or isn’t incontinent anymore.  

How Long Do Dogs With Cushing’s Disease Live?

Depending on the dog’s health status and the cause of Cushing’s disease, the prognosis varies.

Despite having mild symptoms, some dogs may live for years after being diagnosed. Despite being diagnosed with Cushing’s disease, most dogs live for several years after having regular checkups and the proper medication for the symptoms.

Others, however, may be suffering from a more serious condition that cannot be treated with surgery or radiation. The majority of these dogs do not live long with this disease.

Also Read: Previcox killed my dog – What You Should Know

How Can Dog With Cushing’s Disease Be Treat?

Treatment for Cushing’s disease is not one size fits all. The symptoms of this disorder can, however, be controlled with a few common treatment options.

The following are among them:


Cushing’s disease can be treated with a variety of medications. In addition to reducing excessive thirst, urination, and appetite, these medications can also prevent hair loss and muscle wasting.


Cushing’s disease can also be treated with this type of medication. This type of medication can also improve hair growth and reduce cortisol production. Both pills and injections are available for this medication.


Typically, the medication is given to dogs whose adrenal glands have both been affected by the disease. It works by blocking the production of cortisol and can either be taken orally or injected.

Radiation therapy

Cushing’s disease can also be treated with radiotherapy, though not as widely as surgery or medication. Pituitary gland tumors and adrenal gland tumors can also be treated using radiation therapy.

Radiation therapy, however, does not always work and can cause side effects including pain, nausea, and vomiting. Cancer recurrence may also result from radiation.

Cushing’s disease is caused by iatrogenic causes

Cushing’s disease of this type has to be treated by stopping the steroid. Slowly and cautiously stopping the steroid will prevent complications. It is not uncommon, however, for the disease to recur.

The steroid may adversely affect the adrenal glands.ands. Adrenal replacement therapy is often necessary to restore adrenal production.

Cushing’s disease can also be treated with alternative treatments, including dietary changes.

According to recommendations, you should feed your dog more protein and eat foods rich in fat and fiber. Symptoms will be relieved. This treatment is, however, not well supported by evidence. If you plan to change your pet’s diet, speak to your veterinarian first.


Some tumors or glands that overproduce cortisol must be removed by surgery. Surgical treatments for Cushing’s disease are not always effective.  A large tumor may not be operable due to its size or inability to be operated on.

Also Read: Vetmedin killed my dog – How To Handle It?

Cushing’s Disease In Dogs: How Far Along Is It?

Your dog may become weak and lethargic as Cushing’s disease progresses.

Skin lesions may develop, they may stop eating and drinking, and they may become less social.

All of these signs were evident in my own dog’s final weeks before he was euthanized, but I was too late.

Also Read: Can Cytopoint kill my dog? All You Need To Know

Final thought

Dogs with Cushing’s disease are treated with Vetoryl. By blocking cortisol production, this steroid works. In turn, the adrenal glands make less cortisol, thereby helping to reduce symptoms like excessive thirst and urination.

When not used correctly, Vetoryl can cause serious side effects and is often considered a last-resort treatment option. High blood pressure and heart failure can result from sodium retention caused by the drug. Diabetes, osteoporosis, muscle weakness, and kidney impairment can also be caused by venetol.

Speak with your veterinarian if you have any concerns about the management plan for Cushing’s disease for your dog.


1 2

Leave a Comment